Final Draft International Standard
ISO/PRF 7102
Infant formula — Determination of β-galactooligosaccharides — Ultra high performance liquid chromatography (UHPLC) with fluorescence detection after pre-column derivatization
Reference number
ISO/PRF 7102
Edition 1
Final Draft
International Standard
ISO/PRF 7102
Under development (Edition 1, 2024)
This draft is in the approval phase.


This document specifies a method for the determination of β-galactooligosaccharides (GOS) in infant formula (both powder and liquid) containing 0,2 g/100 g to 3,0 g/100 g of GOS in the product as prepared ready for consumption.

The method has been validated in a multi laboratory study with reconstituted infant formula at levels of 0,236 g/100 g, 0,594 g/100 g, 0,616 g/100 g and 0,688 g/100 g and infant formula RTF at levels of 0,316 g/100 g and 0,858 g/100 g. During the single laboratory validation study spike-recovery experiments were performed up to 3 g/100 g in reconstituted infant formula powders (milk-based, partially hydrolysed milk-based and soy-based), and reconstituted adult nutritional powders.

General information

  •  : Under development
     : 2024-08
    : Proof sent to secretariat or FDIS ballot initiated: 8 weeks [50.20]
  •  : 1
     : 19
  • ISO/TC 34/SC 5
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